The player returns as the role of the pilot of the Vic Viper spaceship to battle the second onslaughts of the Bacterion Empire, under the new leadership of Gofer, the giant head. Gradius II has kept the gameplay from the original game, but infused it with enhancements brought from the spin-off, Salamander (Life Force). This is primarily evident in two of the weapons configurations that are selectable. Another first in the series was the inclusion of the "boss rush" (also known as "boss parade" or "boss alley"), a level designed entirely with only boss confrontations.